Comparison of Energy Dependence of PAGAT Polymer Gel Dosimeter with Electron and Photon Beams using Magnetic Resonance Imaging

نویسنده

  • B. Azadbakht
چکیده

The purpose of this study was to evaluate dependence of PAGAT polymer gel dosimeter 1/T2 on different electron and photon energies for a standard clinically used Co therapy unit and an electa linear accelerator.Using MRI, the formulation to give the maximum change in the transverse relaxation rate R2(1/T2) was determined to be 4.5% N,N'-methylen-bis-acrylamide(bis), 4.5% acrylamid(AA), 5% gelatine, 5 mM tetrakis (hydroxymethyl) phosphonium chloride (THPC), 0.01 mM hydroquinone (HQ) and 86% HPLC(Water). When the preparation of final polymer gel solution is completed, it is transferred into phantoms and allowed to set by storage in a refrigerator at about 4°C. The optimal post-manufacture irradiation and post imaging times were both determined to be 24 h. The sensitivity of PAGAT polymer gel dosimeter with irradiation of photon and electron beams was represented by the slope of calibration curve in the linear region measured for each modality. The response of PAGAT gel with photon and electron beams is very similar in the lower dose region. The R2-dose response was linear up to 30 Gy and the R2-dose response of the PAGAT polymer gel dosimeter is linear between 10 to 30 Gy. In electron beams the R2-dose response for doses less than 3 Gy is not exact, but in photon beams the R2-dose response for doses less than 2Gy is not exact. Dosimeter energy dependence was studied for electron energies of 4, 12 and 18MeV and photon energies of 1.25, 4, 6 and 18 MV. Evaluation of dosimeters were performed on Siemens Symphony, Germany 1.5T Scanner in the head coil. In this study no trend in polymer-gel dosimeter 1/T2 dependence was found on mean energy for electron and photon beams.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Verification of the PAGAT polymer gel dosimeter by photon beams using magnetic resonance imaging

Background: In this work investigation of the normoxic PAGAT polymer gel dosimeter such as sensitivity, the R2-dose response with post time and the percentage depth dose (PDD) of PAGAT polymer gel dosimeter have been undertaken. Materials and Methods: Using MRI, the formulation to give the maximum change in the transverse relaxation rate R2 was determined to be 4.5% N,N'-methylenbis- ...

متن کامل

Determination of Percentage Depth Dose (Pdd) of Pagat Gel Dosimeter By Electron Beams

Background: The purpose of this study was to determine the percentage depth dose (PDD) of PAGAT normoxic polymer gel dosimeter by electron beams using MRI technique for a standard clinically used Co-60 therapy unit and an electa linear accelerator. Materials and Methods: Using MRI, the formulation to give the maximum change in the transverse relaxation rate R2(1/T2) was determined to be 4.5% N,...

متن کامل

Verification of dose rate and energy dependence of MAGICA polymer gel dosimeter with electron beams

Background: The purpose of this study was to evaluate the dependency of MAGICA polymer gel dosimeter response (R2) on different electron energies as well as on different mean dose rate for a standard clinically used linear accelerator. Materials and Methods: The sensitivity of the dosimeter was represented by the slope of calibration curve in the linear region measured for each modalit...

متن کامل

Evaluation of Gold Nanoparticle Size Effect on Dose Enhancement Factor in Megavoltage Beam Radiotherapy Using MAGICA Polymer Gel Dosimeter

Background: Gold nanoparticles (GNPs) are among the most promising radiosensitive materials in radiotherapy. Studying the effective sensitizing factors such as nanoparticle size, concentration, surface features, radiation energy and cell type can help to optimize the effect and possible clinical application of GNPs in radiation therapy. In this study, the radiation sensitive polymer gel was use...

متن کامل

An investigation into the effect of magnetic resonance imaging (MRI) echo time spacing and number of echoes on the sensitivity and dose resolution of PAGATUG polymer-gel dosimeter

Background: There are various methods to read out responses of a polymer-gel dosimeter, among which the Magnetic Resonance Imaging (MRI) technique is the most common one. Optimizing imaging protocols can have significant effect on the sensitivity and the dose resolution of polymer gel dosimeters. This study has investigated the effects of the number of echoes (NOE) and the echo time spacing (ES...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012